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BIOENGR M296B

Bruinwalk
Main Course

Optimal Parameter Estimation and Experiment Design for Biomedical Systems

4 units
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Description

(Same as Biomathematics M270, Computer Science M296B, and Medicine M270D.) Lecture, four hours; outside study, eight hours. Requisite: course CM286 or M296A or Biomathematics 220. Estimation methodology and model parameter estimation algorithms for fitting dynamic system models to biomedical data. Model discrimination methods. Theory and algorithms for designing optimal experiments for developing and quantifying models, with special focus on optimal sampling schedule design for kinetic models. Exploration of PC software for model building and optimal experiment design via applications in physiology and pharmacology. Letter grading.

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